About this NAD+ readout.

What Legal NAD is

Legal NAD is a signal-clean readout of the peer-reviewed research on NAD+ and its precursors, rendered in plain English. We read the studies, log what they measured, tag each finding by route and by evidence strength, and cite every figure to source. The format is deliberately an instrument readout rather than an opinion column: confirmed findings, preclinical signals, and honest gaps, each in its own panel.

It runs no clinic and employs no clinicians; it treats no one and gives no medical advice, and it makes, sells, and ships nothing. It reads the studies and reports them — that is the entire remit.

What the name means

The word 'legal' in the name is editorial framing, not a claim about services or a legal opinion. It points at a real feature of this subject: NAD+ and its common precursors are sold as dietary supplements rather than approved drugs, and the regulatory status of one precursor — NMN — is genuinely contested in the U.S. marketplace ^[13]. The name marks the position this publisher occupies relative to that literature — reading the supplement-and-regulatory record straight — not a service we offer. We do not sell NAD+, advise on buying it, or operate any pathway to obtain it.

How we handle accuracy

Two disciplines govern every page. First, the NAD+-versus-precursor distinction is kept exact: oral NAD+ is poorly absorbed, so a trial of NMN or NR is never described as 'taking NAD+', and every route-specific figure carries a channel tag (ORAL-PRECURSOR, IV, INJECTABLE). Second, we describe only what specific cited studies measured, in research framing — 'a trial of 250 mg/day NMN raised blood NAD+ and improved muscle insulin sensitivity' ^[11] — never a recommendation to use any product or dose. We do not claim NAD+ or any precursor treats, reverses, cures or prevents aging or any disease. Where the evidence is thin — IV NAD+, hard clinical endpoints, tissue-level NAD+ — we say so, citing the 2025 review that reached the same conclusion ^[14].

Corrections

If a citation is misattributed or a figure is wrong, we want to fix it. The studies cited here are real, indexed and linked; if you find an error, the contact page is the way to flag it. This is a digest of the literature, and the literature is the authority — not this site.